A Cross Sectional Study
Why was this study conducted?
This research is a 10-year follow-up to a previous study by Block and colleagues, which found healthier cardiovascular biomarkers and a lower prevalence of Type 2 diabetes and hypertension among long-term multiple dietary supplement (LTMDS) users compared to a NHANES cohort of non-users or single multivitamin users. Of the original 278 participants, 235 enrolled in this follow-up to evaluate if the previously observed healthier cardiometabolic status continued with aging. At the time of follow-up, the average age of the LTMDS cohort was 73, approximately 10 years older than the four NHANES comparison groups (2007-2010).
What were the findings?
After more than 30 years of consistent supplement use, the long-term multiple dietary supplement users maintained better cardiometabolic health compared to a non-supplementing NHANES cohort. Specifically, they showed higher HDL cholesterol, lower LDL cholesterol, and lower fasting blood glucose levels. Additionally, the LTMDS group required significantly fewer medications across nearly all categories studied.
These findings reinforce earlier results from the Block study, suggesting that consistent long-term use of multiple dietary supplements may confer sustained cardiometabolic benefits. The results also align with prior observational evidence linking dietary supplement use to improved cardiometabolic risk factors.
In Plain Terms:
In plain terms:
This study was conducted to see if taking multiple dietary supplements over many years can help maintain better heart health and lower the risk of diabetes as people age. Researchers followed a group of individuals who had been using several dietary supplements daily for over 30 years, comparing their health with others who took fewer or no supplements.
After 10 years, the group taking multiple supplements consistently had healthier cholesterol levels, better blood sugar control, and needed fewer medications than those who didn’t regularly use supplements. These findings suggest that regularly taking multiple dietary supplements over the long-term may help support heart health and reduce diabetes risk.
A beneficial cardiometabolic health profile associated with dietary supplement use: A cross-sectional study
Authors: Paul F. Jacques,Gail Rogers
Int J Vitam Nutr Res. 2021 Mar 1:1-11. doi: 10.1024/0300-9831/a000701. Epub ahead of print. PMID: 33646010.
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